Collaboration

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics
Acute myeloid leukemia (AML) comprises diverse genomic subgroups and remains hard to treat in most patients. Despite breakthroughs in …
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Novel tumor-specific antigens for acute myeloid leukemia (aml) and uses thereof
Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly because of the lack of actionable immune …
Patent Application Publication
Proteogenomic-based method for identifying tumor-specific antigens
T cells, notably CD8 T cells, are known to be essential players in tumor eradication as the presence of tumor-infiltrating lymphocytes …
Patent Application Publication
Transposable elements regulate thymus development and function
Transposable elements (TE) are repetitive sequences representing ~45% of the human and mouse genomes and are highly expressed by …
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Towards Computing Attributions for Dimensionality Reduction Techniques
We describe the problem of computing local feature attributions for dimensionality reduction methods. We use one such method that is …
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Towards Computing Attributions for Dimensionality Reduction Techniques
Unmutated tumor antigens are abundant and contribute to tumor control in melanoma
Recognition of MHC-I-associated tumor antigens (TAs) by CD8+ T cells is central to antitumor immunity. Owing to the elevated tumor …
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Identification of Novel Cell Surface Therapeutic Targets for KMT2A-Rearranged Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a highly heterogeneous disease that represents 80% of adult leukemias and is characterized by …
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IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy with variable clinical outcomes depending on baseline patient …
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Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia
Glucocorticoids (GCs) are Glucocorticoid Receptor (GR) agonists that are extensively used in clinic, from management of autoimmune and …
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Novel tumor-specific antigens for ovarian cancer and uses thereof
Ovarian cancer, notably high-grade serous ovarian cancer (HGSC), the principal cause of death from gynecological malignancies in the …
Patent Application Publication