Pierre Thibault

Récents

• Immunotherapeutic targeting of surfaceome heterogeneity in AML
• Transposable elements regulate thymus development and function
• BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
• Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
• Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells
• The tumor-specific antigen landscape of acute myeloid leukemia
• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• CAMAP - Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
• Most non-canonical proteins uniquely populate the proteome or immunopeptidome
• MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• Noncoding regions are the main source of targetable tumor-specific antigens
• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• Occurrence and Detection of Phosphopeptide Isomers in Large-Scale Phosphoproteomics Experiments
• ProteoConnections - a bioinformatics platform to facilitate proteome and phosphoproteome analyses
• The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
• Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules
• The phagosomal proteome in interferon-gamma-activated macrophages
• The MHC class I peptide repertoire is molded by the transcriptome