Patrick Gendron

Récents

• Immunotherapeutic targeting of surfaceome heterogeneity in AML
• Transposable elements regulate thymus development and function
• BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
• Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia
• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A NPM1 and FLT3-ITD triple-mutated AML
• Targeted variant detection using unaligned RNA-Seq reads
• Noncoding regions are the main source of targetable tumor-specific antigens
• Target variant detection in leukemia using unaligned RNA-Seq reads
• Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
• GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
• RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature
• EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
• The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
• A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
• Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans