Jean-Philippe Laverdure

Récents

• Transposable elements regulate thymus development and function
• BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
• Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
• The tumor-specific antigen landscape of acute myeloid leukemia
• Two types of human TCR differentially regulate reactivity to self and non-self antigens
• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Noncoding regions are the main source of targetable tumor-specific antigens
• Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus
• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation