Claude Perreault

Récents

• Transposable elements regulate thymus development and function
• BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
• Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
• The tumor-specific antigen landscape of acute myeloid leukemia
• Two types of human TCR differentially regulate reactivity to self and non-self antigens
• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• CAMAP - Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
• Most non-canonical proteins uniquely populate the proteome or immunopeptidome
• UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections
• Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
• MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Holographic Neural Architectures
• Noncoding regions are the main source of targetable tumor-specific antigens
• Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus
• Warp - a method for neural network interpretability applied to gene expression profiles
• Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• pyGeno - A Python package for precision medicine and proteogenomics
• Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• Transcriptome sequencing of neonatal thymic epithelial cells
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
• A comprehensive map of the mTOR signaling network
• Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules
• The MHC class I peptide repertoire is molded by the transcriptome