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2024
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Marie-Eve Bordeleau
,
Éric Audemard
,
Arnaud Métois
,
Louis Théret
,
Véronique Lisi
,
Azer Farah
,
Jean-François Spinella
,
Jalila Chagraoui
,
Ossama Moujaber
,
Léo Aubert
,
Banafsheh Khakipoor
,
Laure Mallinger
,
Isabel Boivin
,
Nadine Mayotte
,
Azadeh Hajmirza
,
Éric Bonneil
,
François Béliveau
,
Sybille Pfammatter
,
Albert Feghaly
,
Geneviève Boucher
,
Patrick Gendron
,
Pierre Thibault
,
Frédéric Barabé
,
Sébastien Lemieux
,
Philippe P. Roux
,
Guy Sauveageau
(2024).
Immunotherapeutic targeting of surfaceome heterogeneity in AML
. Cell Reports.
Cite
DOI
Jean-David Larouche
,
M. Céline Laumont
,
Assya Trofimov
,
Krystel Vincent
,
Leslie Hesnard
,
Sylvie Brochu
,
Caroline Côté
,
Juliette Humeau
,
Éric Bonneil
,
Joël Lanoix
,
Chantal Durette
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
R. Ellen Richie
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2024).
Transposable elements regulate thymus development and function
. eLife.
Cite
DOI
Maria Virginia Ruiz Cuevas
,
Marie-Pierre Hardy
,
Jean-David Larouche
,
Anca Apavaloaei
,
Eralda Kina
,
Krystel Vincent
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Pierre Thibault
,
Sébastien Lemieux
,
Claude Perreault
,
Gregory Ehx
(2023).
BamQuery: a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
. Genome Biology.
Cite
Code
DOI
BamQuery
Matthew Scicluna
,
Jean-Christophe Grenier
,
Raphaël Poujol
,
Sébastien Lemieux
,
G Julie Hussin
(2023).
Toward computing attributions for dimensionality reduction techniques
. Bioinformatics Advances.
Cite
DOI
Jérémie Zumer
,
Sébastien Lemieux
(2023).
Pepid - a Highly Modifiable Bioinformatics-Oriented Peptide Search Engine
.
Cite
DOI
Jérémie Zumer
,
Sébastien Lemieux
(2023).
Mining Mass Spectra for Peptide Facts
.
Cite
DOI
Maria Virginia Ruiz Cuevas
,
Marie-Pierre Hardy
,
Jean-David Larouche
,
Anca Apavaloaei
,
Eralda Kina
,
Krystel Vincent
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Pierre Thibault
,
Sébastien Lemieux
,
Claude Perreault
,
Gregory Ehx
(2023).
BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
. Genome Biology.
Cite
DOI
Jana Krosl
,
Marie-Eve Bordeleau
,
Céline Moison
,
Tara Macrae
,
Isabel Boivin
,
Nadine Mayotte
,
Deanne Gracias
,
Irène Baccelli
,
Vincent-Philippe Lavallée
,
Richard Bisaillon
,
Bernhard Lehnertz
,
Rodrigo Mendoza-Sanchez
,
Réjean Ruel
,
Thierry Bertomeu
,
Jasmin Coulombe-Huntington
,
Geneviève Boucher
,
Nandita Noronha
,
Caroline Pabst
,
Mike Tyers
,
Patrick Gendron
,
Sébastien Lemieux
,
Frédéric Barabé
,
Anne Marinier
,
Josée Hébert
,
Guy Sauvageau
(2022).
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
. Blood Advances.
Cite
DOI
Assya Trofimov
,
Philippe Brouillard
,
Jean-David Larouche
,
Jonathan Séguin
,
Jean-Philippe Laverdure
,
Ann Brasey
,
Gregory Ehx
,
Denis-Claude Roy
,
Lambert Busque
,
Silvy Lachance
,
Sébastien Lemieux
,
Claude Perreault
(2022).
Two types of human TCR differentially regulate reactivity to self and non-self antigens
. iScience.
Cite
DOI
Gregory Ehx
,
Krystel Vincent
,
Jean-David Larouche
,
Chantal Durette
,
Jean-Philippe Laverdure
,
Joël Lanoix
,
Éric Bonneil
,
Marie-Pierre Hardy
,
Caroline Côté
,
Nandita Noronha
,
Leslie Hesnard
,
Qingchuan Zhao
,
M Céline Laumont
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2022).
The tumor-specific antigen landscape of acute myeloid leukemia
. Molecular Immunology.
Cite
DOI
Zhaoguan Wu
,
Éric Bonneil
,
Michael Belford
,
Cornelia Boeser
,
Maria Virginia Ruiz Cuevas
,
Sébastien Lemieux
,
Jean-Jacques Dunyach
,
Pierre Thibault
(2022).
Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells
. Analytical Chemistry.
Cite
DOI
T. F. Diogo Veiga
,
Mathieu Tremblay
,
Bastien Gerby
,
Sabine Herblot
,
André Haman
,
Patrick Gendron
,
Sébastien Lemieux
,
Carlos Juan Zúñiga-Pflücker
,
Josée Hébert
,
Paul Joseph Cohen
,
Trang Hoang
(2022).
Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia
. Frontiers in Immunology.
Cite
Anca Apavaloaei
,
Leslie Hesnard
,
Marie-Pierre Hardy
,
Basma Benabdallah
,
Gregory Ehx
,
Catherine Thériault
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Joël Lanoix
,
Mathieu Courcelles
,
Nandita Noronha
,
Dev Kapil Chauhan
,
Sébastien Lemieux
,
Christian Beauséjour
,
Mick Bhatia
,
Pierre Thibault
,
Claude Perreault
(2022).
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
. Cell Reports.
Cite
DOI
Léonard Sauvé
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
(2022).
Baseline Acute Myeloid Leukemia Prognosis Models using Transcriptomic and Clinical Profiles by Studying the Impacts of Dimensionality Reductions and Gene Signatures on Cox-Proportional Hazard
.
Cite
DOI
Maude Dumont-Lagacé
,
Qi Li
,
Mégane Tanguay
,
Jalila Chagraoui
,
Tibila Kientega
,
B. Guillaume Cardin
,
Ann Brasey
,
Assya Trofimov
,
Cédric Carli
,
Imran Ahmad
,
M. Nadia Bambace
,
Léa Bernard
,
L. Thomas Kiss
,
Jean Roy
,
Denis-Claude Roy
,
Sébastien Lemieux
,
Claude Perreault
,
Francis Rodier
,
Frédéric Simon Dufresne
,
Lambert Busque
,
Silvy Lachance
,
Guy Sauvageau
,
Sandra Cohen
,
Jean-Sébastien Delisle
(2021).
UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections
. Transplantation and Cellular Therapy.
Cite
DOI
Valérie Janelle
,
Mathieu Neault
,
Marie-Ève Lebel
,
Maurice Dave Sousa De
,
Salix Boulet
,
Ludovic Durrieu
,
Cédric Carli
,
Chloé Muzac
,
Sébastien Lemieux
,
Nathalie Labrecque
,
J. Heather Melichar
,
A. Frédérick Mallette
,
Jean-Sébastien Delisle
(2021).
p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells
. Frontiers in Immunology.
Cite
Maria Virginia Ruiz Cuevas
,
Marie-Pierre Hardy
,
Jaroslav Hollý
,
Éric Bonneil
,
Chantal Durette
,
Mathieu Courcelles
,
Joël Lanoix
,
Caroline Côté
,
M. Louis Staudt
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
,
W. Jonathan Yewdell
(2021).
Most non-canonical proteins uniquely populate the proteome or immunopeptidome
. Cell Reports.
Cite
DOI
Michael Lang
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
,
H. Ma'n Zawati
(2021).
Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers Clinicians and Patients - Scoping Literature Review
. Journal of Medical Internet Research.
Cite
DOI
Tariq Daouda
,
Maude Dumont-Lagacé
,
Albert Feghaly
,
Yahya Benslimane
,
Rébecca Panes
,
Mathieu Courcelles
,
Mohamed Benhammadi
,
Lea Harrington
,
Pierre Thibault
,
François Major
,
Yoshua Bengio
,
Étienne Gagnon
,
Sébastien Lemieux
,
Claude Perreault
(2021).
CAMAP - Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
. PLOS Computational Biology.
Cite
DOI
Gregory Ehx
,
Jean-David Larouche
,
Chantal Durette
,
Jean-Philippe Laverdure
,
Leslie Hesnard
,
Krystel Vincent
,
Marie-Pierre Hardy
,
Catherine Thériault
,
Caroline Rulleau
,
Joël Lanoix
,
Éric Bonneil
,
Albert Feghaly
,
Anca Apavaloaei
,
Nandita Noronha
,
M. Céline Laumont
,
Jean-Sébastien Delisle
,
Luca Vago
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2021).
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
. Immunity.
Cite
DOI
Jean-David Larouche
,
Assya Trofimov
,
Leslie Hesnard
,
Gregory Ehx
,
Qingchuan Zhao
,
Krystel Vincent
,
Chantal Durette
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
Éric Bonneil
,
Caroline Côté
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2020).
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
. Genome Medicine.
Cite
DOI
Valérie Camille Jamblinne De
,
Barbara Decelle
,
Mehrnoush Dehghani
,
Mathieu Joseph
,
Neera Sriskandarajah
,
Kévin Leguay
,
Basile Rambaud
,
Sébastien Lemieux
,
P. Philippe Roux
,
R. David Hipfner
,
Sébastien Carréno
(2020).
STRIPAK regulates Slik localization to control mitotic morphogenesis and epithelial integrity
. Journal of Cell Biology.
Cite
DOI
Maude Dumont-Lagacé
,
Tariq Daouda
,
Lucyle Depoërs
,
Jérémie Zumer
,
Yahya Benslimane
,
Sylvie Brochu
,
Lea Harrington
,
Sébastien Lemieux
,
Claude Perreault
(2020).
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration
. Frontiers in Immunology.
Cite
Qingchuan Zhao
,
Jean-Philippe Laverdure
,
Joël Lanoix
,
Chantal Durette
,
Caroline Côté
,
Éric Bonneil
,
M. Céline Laumont
,
Patrick Gendron
,
Krystel Vincent
,
Mathieu Courcelles
,
Sébastien Lemieux
,
G. Douglas Millar
,
S. Pamela Ohashi
,
Pierre Thibault
,
Claude Perreault
(2020).
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
. Cancer Immunology Research.
Cite
DOI
Mathieu Courcelles
,
Chantal Durette
,
Tariq Daouda
,
Jean-Philippe Laverdure
,
Krystel Vincent
,
Sébastien Lemieux
,
Claude Perreault
,
Pierre Thibault
(2020).
MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
. Journal of Proteome Research.
Cite
DOI
Laura Simon
,
Jean-François Spinella
,
Chi-Yuan Yao
,
Vincent-Philippe Lavallée
,
Isabel Boivin
,
Geneviève Boucher
,
Éric Audemard
,
Marie-Eve Bordeleau
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
(2020).
High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
. Blood.
Cite
DOI
Sandra Cohen
,
Jean Roy
,
Silvy Lachance
,
Jean-Sébastien Delisle
,
Anne Marinier
,
Lambert Busque
,
Denis-Claude Roy
,
Frédéric Barabé
,
Imran Ahmad
,
Nadia Bambace
,
Léa Bernard
,
Thomas Kiss
,
Philippe Bouchard
,
Pierre Caudrelier
,
Sévérine Landais
,
Fannie Larochelle
,
Jalila Chagraoui
,
Bernhard Lehnertz
,
Sophie Corneau
,
Elisa Tomellini
,
van A. J. Jeroen Kampen
,
J. Jan Cornelissen
,
Maude Dumont-Lagacé
,
Mégane Tanguay
,
Qi Li
,
Sébastien Lemieux
,
W. Peter Zandstra
,
Guy Sauvageau
(2020).
Hematopoietic stem cell transplantation using single UM171-expanded cord blood - a single-arm phase 1–2 safety and feasibility study
. The Lancet Haematology.
Cite
DOI
Richard Bisaillon
,
Céline Moison
,
Clarisse Thiollier
,
Jana Krosl
,
Marie-Eve Bordeleau
,
Bernhard Lehnertz
,
Vincent-Philippe Lavallée
,
Tara Macrae
,
Nadine Mayotte
,
Caroline Labelle
,
Geneviève Boucher
,
Jean-François Spinella
,
Isabel Boivin
,
Giovanni D'Angelo
,
Sylvie Lavallée
,
Anne Marinier
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
(2020).
Genetic characterization of ABT-199 sensitivity in human AML
. Leukemia.
Cite
DOI
Assya Trofimov
,
Paul Joseph Cohen
,
Yoshua Bengio
,
Claude Perreault
,
Sébastien Lemieux
(2020).
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
. Bioinformatics.
Cite
DOI
Mandana Samiei
,
Tobias Würfl
,
Tristan Deleu
,
Martin Weiss
,
Francis Dutil
,
Thomas Fevens
,
Geneviève Boucher
,
Sébastien Lemieux
,
Paul Joseph Cohen
(2019).
The TCGA Meta-Dataset Clinical Benchmark
.
Cite
Éric Audemard
,
Patrick Gendron
,
Albert Feghaly
,
Vincent-Philippe Lavallée
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
(2019).
Targeted variant detection using unaligned RNA-Seq reads
. Life Science Alliance.
Cite
DOI
Irène Baccelli
,
Yves Gareau
,
Bernhard Lehnertz
,
Stéphane Gingras
,
Jean-François Spinella
,
Sophie Corneau
,
Nadine Mayotte
,
Simon Girard
,
Mélanie Frechette
,
Valérie Blouin-Chagnon
,
Koryne Leveillé
,
Isabel Boivin
,
Tara Macrae
,
Jana Krosl
,
Clarisse Thiollier
,
Vincent-Philippe Lavallée
,
Evgeny Kanshin
,
Thierry Bertomeu
,
Jasmin Coulombe-Huntington
,
Corinne St-Denis
,
Marie-Eve Bordeleau
,
Geneviève Boucher
,
P. Philippe Roux
,
Sébastien Lemieux
,
Mike Tyers
,
Pierre Thibault
,
Josée Hébert
,
Anne Marinier
,
Guy Sauvageau
(2019).
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
. Cancer Cell.
Cite
DOI
Swati Garg
,
Armando Reyes-Palomares
,
Lixiazi He
,
Anne Bergeron
,
Vincent-Philippe Lavallée
,
Sébastien Lemieux
,
Patrick Gendron
,
Christian Rohde
,
Jianglong Xia
,
Prarabdha Jagdhane
,
Carsten Müller-Tidow
,
B. Daniel Lipka
,
Suzan Imren
,
Keith R. Humphries
,
Claudia Waskow
,
Binje Vick
,
Irmela Jeremias
,
Guillaume Richard-Carpentier
,
Josée Hébert
,
Guy Sauvageau
,
B. Judith Zaugg
,
Frédéric Barabé
,
Caroline Pabst
(2019).
Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A NPM1 and FLT3-ITD triple-mutated AML
. Blood.
Cite
DOI
Caroline Labelle
,
Anne Marinier
,
Sébastien Lemieux
(2019).
Enhancing the drug discovery process - Bayesian inference for the analysis and comparison of dose–response experiments
. Bioinformatics.
Cite
DOI
Céline Moison
,
Vincent-Philippe Lavallée
,
Clarisse Thiollier
,
Bernhard Lehnertz
,
Isabel Boivin
,
Nadine Mayotte
,
Yves Gareau
,
Mélanie Frechette
,
Valérie Blouin-Chagnon
,
Sophie Corneau
,
Sylvie Lavallée
,
Sébastien Lemieux
,
Anne Marinier
,
Josée Hébert
,
Guy Sauvageau
(2019).
Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition
. Blood Advances.
Cite
DOI
Vincent-Philippe Lavallée
,
Jalila Chagraoui
,
Tara Macrae
,
Miriam Marquis
,
Arnaud Bonnefoy
,
Jana Krosl
,
Sébastien Lemieux
,
Anne Marinier
,
Caroline Pabst
,
Georges-Étienne Rivard
,
Josée Hébert
,
Guy Sauvageau
(2018).
Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin
. Leukemia.
Cite
DOI
Trofimov Assya
,
Dutil Francis
,
Perreault Claude
,
Lemieux Sebastien
,
Bengio Yoshua
,
Cohen Joseph Paul
(2018).
Towards the Latent Transcriptome
.
Cite
DOI
Olivier Eric Audemard
,
Patrick Gendron
,
Vincent-Philippe Lavallée
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
(2018).
Target variant detection in leukemia using unaligned RNA-Seq reads
.
Cite
DOI
M. Céline Laumont
,
Krystel Vincent
,
Leslie Hesnard
,
Éric Audemard
,
Éric Bonneil
,
Jean-Philippe Laverdure
,
Patrick Gendron
,
Mathieu Courcelles
,
Marie-Pierre Hardy
,
Caroline Côté
,
Chantal Durette
,
Charles St-Pierre
,
Mohamed Benhammadi
,
Joël Lanoix
,
Suzanne Vobecky
,
Elie Haddad
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2018).
Noncoding regions are the main source of targetable tumor-specific antigens
. Science Translational Medicine.
Cite
DOI
Tariq Daouda
,
Jérémie Zumer
,
Claude Perreault
,
Sébastien Lemieux
(2018).
Holographic Neural Architectures
.
Cite
Miriam Marquis
,
Cyrielle Beaubois
,
Vincent-Philippe Lavallée
,
Michal Abrahamowicz
,
Coraline Danieli
,
Sébastien Lemieux
,
Imran Ahmad
,
Andrew Wei
,
B. Stephen Ting
,
Shaun Fleming
,
Anthony Schwarer
,
David Grimwade
,
William Grey
,
K. Robert Hills
,
Paresh Vyas
,
Nigel Russell
,
Guy Sauvageau
,
Josée Hébert
(2018).
High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia
. Blood Cancer Journal.
Cite
DOI
Assya Trofimov
,
Sébastien Lemieux
,
Claude Perreault
(2017).
Warp - a method for neural network interpretability applied to gene expression profiles
.
Cite
DOI
Lemieux Sebastien
,
Sargeant Tobias
,
Laperrière David
,
Ismail Houssam
,
Boucher Geneviève
,
Rozendaal Marieke
,
Lavallée Vincent-Philippe
,
Ashton-Beaucage Dariel
,
Wilhelm Brian
,
Hébert Josée
,
Mader Sylvie
,
Sauvageau Guy
(2017).
MiSTIC an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets
. Nucleic Acids Research.
Cite
DOI
Maude Dumont-Lagacé
,
Hervé Gerbe
,
Tariq Daouda
,
Jean-Philippe Laverdure
,
Sylvie Brochu
,
Sébastien Lemieux
,
Étienne Gagnon
,
Claude Perreault
(2017).
Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus
. Frontiers in Immunology.
Cite
DOI
Laura Simon
,
Vincent-Philippe Lavallée
,
Marie-Eve Bordeleau
,
Jana Krosl
,
Irène Baccelli
,
Geneviève Boucher
,
Bernhard Lehnertz
,
Jalila Chagraoui
,
Tara Macrae
,
Réjean Ruel
,
Yves Chantigny
,
Sébastien Lemieux
,
Anne Marinier
,
Josée Hébert
,
Guy Sauvageau
(2017).
Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity
. Clinical Cancer Research.
Cite
DOI
The Theano Development Team
,
Al-Rfou Rami
,
Alain Guillaume
,
Almahairi Amjad
,
Angermueller Christof
,
Bahdanau Dzmitry
,
Ballas Nicolas
,
Bastien Frédéric
,
Bayer Justin
,
Belikov Anatoly
,
Belopolsky Alexander
,
Bengio Yoshua
,
Bergeron Arnaud
,
Bergstra James
,
Bisson Valentin
,
Snyder Josh Bleecher
,
Bouchard Nicolas
,
Boulanger-Lewandowski Nicolas
,
Bouthillier Xavier
,
de Brébisson Alexandre
,
Breuleux Olivier
,
Carrier Pierre-Luc
,
Cho Kyunghyun
,
Chorowski Jan
,
Christiano Paul
,
Cooijmans Tim
,
Côté Marc-Alexandre
,
Côté Myriam
,
Courville Aaron
,
Delalleau Olivier
,
Demouth Julien
,
Desjardins Guillaume
,
Dieleman Sander
,
Dinh Laurent
,
Ducoffe Mélanie
,
Dumoulin Vincent
,
Kahou Samira Ebrahimi
,
Erhan Dumitru
,
Fan Ziye
,
Firat Orhan
,
Germain Mathieu
,
Glorot Xavier
,
Goodfellow Ian
,
Graham Matt
,
Gulcehre Caglar
,
Hamel Philippe
,
Harlouchet Iban
,
Heng Jean-Philippe
,
Hidasi Balázs
,
Honari Sina
,
Jain Arjun
,
Jean Sébastien
,
Jia Kai
,
Korobov Mikhail
,
Kulkarni Vivek
,
Lamb Alex
,
Lamblin Pascal
,
Larsen Eric
,
Laurent César
,
Lee Sean
,
Lefrancois Simon
,
Lemieux Simon
,
Léonard Nicholas
,
Lin Zhouhan
,
Lorenz Cory
,
Lowin Jeremiah
,
Ma Qianli
,
Manzagol Pierre-Antoine
,
Mastropietro Olivier
,
Memisevic Roland
,
van Merriënboer Bart
,
Michalski Vincent
,
Mirza Mehdi
,
Orlandi Alberto
,
Pal Christopher
,
Pascanu Razvan
,
Pezeshki Mohammad
,
Raffel Colin
,
Renshaw Daniel
,
Rocklin Matthew
,
Romero Adriana
,
Roth Markus
,
Sadowski Peter
,
Salvatier John
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Savard François
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Schlüter Jan
,
Schulman John
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Schwartz Gabriel
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Serban Iulian Vlad
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Serdyuk Dmitriy
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Shabanian Samira
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Simon Étienne
,
Spieckermann Sigurd
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Subramanyam S. Ramana
,
Sygnowski Jakub
,
Tanguay Jérémie
,
van Tulder Gijs
,
Turian Joseph
,
Urban Sebastian
,
Vincent Pascal
,
Visin Francesco
,
de Vries Harm
,
Warde-Farley David
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Willson Matthew
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Xu Kelvin
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Xue Lijun
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Yao Li
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Zhang Saizheng
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Zhang Ying
(2016).
Theano - A Python framework for fast computation of mathematical expressions
.
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DOI
Vincent-Philippe Lavallée
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Sébastien Lemieux
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Geneviève Boucher
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Patrick Gendron
,
Isabel Boivin
,
N. Richard Armstrong
,
Guy Sauvageau
,
Josée Hébert
(2016).
RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature
. Blood.
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DOI
Tariq Daouda
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Claude Perreault
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Sébastien Lemieux
(2016).
pyGeno - A Python package for precision medicine and proteogenomics
. F1000Research.
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DOI
Caroline Labelle
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Geneviève Boucher
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Sébastien Lemieux
(2016).
myCircos - Facilitating the Creation and Use of Circos Plots Online
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DOI
Caroline Pabst
,
Anne Bergeron
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Vincent-Philippe Lavallée
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Jonathan Yeh
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Patrick Gendron
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L. Gudmundur Norddahl
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Jana Krosl
,
Isabel Boivin
,
Eric Deneault
,
Jessica Simard
,
Suzan Imren
,
Geneviève Boucher
,
Kolja Eppert
,
Tobias Herold
,
K. Stefan Bohlander
,
Keith Humphries
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
,
Frédéric Barabé
(2016).
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
. Blood.
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DOI
M. Céline Laumont
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Tariq Daouda
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Jean-Philippe Laverdure
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Éric Bonneil
,
Olivier Caron-Lizotte
,
Marie-Pierre Hardy
,
P. Diana Granados
,
Chantal Durette
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2016).
Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
. Nature Communications.
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DOI
Alexandre Rouette
,
Assya Trofimov
,
David Haberl
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Geneviève Boucher
,
Vincent-Philippe Lavallée
,
Giovanni D'Angelo
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
,
Claude Perreault
(2016).
Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
. Scientific Reports.
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DOI
Vincent-Philippe Lavallée
,
Jana Krosl
,
Sébastien Lemieux
,
Geneviève Boucher
,
Patrick Gendron
,
Caroline Pabst
,
Isabel Boivin
,
Anne Marinier
,
J. Cynthia Guidos
,
Sylvain Meloche
,
Josée Hébert
,
Guy Sauvageau
(2016).
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
. Blood.
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DOI
Vincent-Philippe Lavallée
,
Irène Baccelli
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Jana Krosl
,
Brian Wilhelm
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Frédéric Barabé
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Patrick Gendron
,
Geneviève Boucher
,
Sébastien Lemieux
,
Anne Marinier
,
Sylvain Meloche
,
Josée Hébert
,
Guy Sauvageau
(2015).
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
. Nature Genetics.
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DOI
Eric Bonneau
,
Nicolas Girard
,
Sébastien Lemieux
,
Pascale Legault
(2015).
The NMR structure of the II–III–VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure
. RNA.
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DOI
Vincent-Philippe Lavallée
,
Patrick Gendron
,
Sébastien Lemieux
,
Giovanni D'Angelo
,
Josée Hébert
,
Guy Sauvageau
(2015).
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
. Blood.
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DOI
Charles St-Pierre
,
Assya Trofimov
,
Sylvie Brochu
,
Sébastien Lemieux
,
Claude Perreault
(2015).
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
. Journal of Immunology (Baltimore Md.: 1950).
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DOI
Bastien Gerby
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S. Cedric Tremblay
,
Mathieu Tremblay
,
Shanti Rojas-Sutterlin
,
Sabine Herblot
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
,
Eric Lécuyer
,
T. F. Diogo Veiga
,
Trang Hoang
(2014).
SCL LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells
. PLoS Genetics.
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DOI
Paola Diana Granados
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Dev Sriranganadane
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Tariq Daouda
,
Antoine Zieger
,
M. Céline Laumont
,
Olivier Caron-Lizotte
,
Geneviève Boucher
,
Marie-Pierre Hardy
,
Patrick Gendron
,
Caroline Côté
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2014).
Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
. Nature Communications.
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DOI
Caroline Pabst
,
Jana Krosl
,
Iman Fares
,
Geneviève Boucher
,
Réjean Ruel
,
Anne Marinier
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Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
(2014).
Identification of small molecules that support human leukemia stem cell activity ex vivo
. Nature Methods.
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DOI
Dariel Ashton-Beaucage
,
M. Christian Udell
,
Patrick Gendron
,
Malha Sahmi
,
Martin Lefrançois
,
Caroline Baril
,
Anne-Sophie Guenier
,
Jean Duchaine
,
Daniel Lamarre
,
Sébastien Lemieux
,
Marc Therrien
(2014).
A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila
. PLoS biology.
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DOI
Charles St-Pierre
,
Sylvie Brochu
,
Ruiz Juan Vanegas
,
Maude Dumont-Lagacé
,
Sébastien Lemieux
,
Claude Perreault
(2013).
Transcriptome sequencing of neonatal thymic epithelial cells
. Scientific Reports.
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DOI
Tara Macrae
,
Tobias Sargeant
,
Sébastien Lemieux
,
Josée Hébert
,
Eric Deneault
,
Guy Sauvageau
(2013).
RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells
. PloS One.
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DOI
Mathieu Courcelles
,
Christophe Frémin
,
Laure Voisin
,
Sébastien Lemieux
,
Sylvain Meloche
,
Pierre Thibault
(2013).
Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions
. Molecular Systems Biology.
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DOI
Nocq Julie
,
Celton Magalie
,
Gendron Patrick
,
Lemieux Sebastien
(2013).
Harnessing virtual machines to simplify next-generation DNA sequencing analysis
. Bioinformatics (Oxford England).
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DOI
Lacombe Julie
,
Krosl Gorazd
,
Tremblay Mathieu
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Gerby Bastien
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Martin Richard
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Lemieux Sebastien
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Hoang Trang
(2013).
Genetic interaction between Kit and Scl
. Blood.
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DOI
Leucegene Project
(2013).
Funding considerations for the disclosure of genetic incidental findings in biobank research
. Clinical Genetics.
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DOI
Philippe Serhal
,
Sébastien Lemieux
(2013).
Correction of spatial bias in oligonucleotide array data
. Advances in Bioinformatics.
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DOI
Mathieu Courcelles
,
Gaëlle Bridon
,
Sébastien Lemieux
,
Pierre Thibault
(2012).
Occurrence and Detection of Phosphopeptide Isomers in Large-Scale Phosphoproteomics Experiments
. Journal of Proteome Research.
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DOI
Paola Diana Granados
,
Wafaa Yahyaoui
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M. Céline Laumont
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Tariq Daouda
,
L. Tara Muratore-Schroeder
,
Caroline Côté
,
Jean-Philippe Laverdure
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2012).
MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
. Blood.
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DOI
Julie Lacroix-Labonté
,
Nicolas Girard
,
Sébastien Lemieux
,
Pascale Legault
(2012).
Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture
. Nucleic Acids Research.
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DOI
Camille Simon
,
Jalila Chagraoui
,
Jana Krosl
,
Patrick Gendron
,
Brian Wilhelm
,
Sébastien Lemieux
,
Geneviève Boucher
,
Pierre Chagnon
,
Simon Drouin
,
Raphaëlle Lambert
,
Claude Rondeau
,
Annie Bilodeau
,
Sylvie Lavallée
,
Martin Sauvageau
,
Josée Hébert
,
Guy Sauvageau
(2012).
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
. Genes & Development.
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DOI
Etienne Caron
,
Krystel Vincent
,
Marie-Hélène Fortier
,
Jean-Philippe Laverdure
,
Alexandre Bramoullé
,
Marie-Pierre Hardy
,
Grégory Voisin
,
P. Philippe Roux
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2011).
The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
. Molecular Systems Biology.
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DOI
Mathieu Courcelles
,
Sébastien Lemieux
,
Laure Voisin
,
Sylvain Meloche
,
Pierre Thibault
(2011).
ProteoConnections - a bioinformatics platform to facilitate proteome and phosphoproteome analyses
. Proteomics.
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DOI
Danielle Verteuil de
,
L. Tara Muratore-Schroeder
,
P. Diana Granados
,
Marie-Hélène Fortier
,
Marie-Pierre Hardy
,
Alexandre Bramoullé
,
Etienne Caron
,
Krystel Vincent
,
Sylvie Mader
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
(2010).
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules
. Molecular & cellular proteomics.
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DOI
Etienne Caron
,
Samik Ghosh
,
Yukiko Matsuoka
,
Dariel Ashton-Beaucage
,
Marc Therrien
,
Sébastien Lemieux
,
Claude Perreault
,
P. Philippe Roux
,
Hiroaki Kitano
(2010).
A comprehensive map of the mTOR signaling network
. Molecular Systems Biology.
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DOI
Matthias Trost
,
Luc English
,
Sébastien Lemieux
,
Mathieu Courcelles
,
Michel Desjardins
,
Pierre Thibault
(2009).
The phagosomal proteome in interferon-gamma-activated macrophages
. Immunity.
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DOI
Katharina Trunk
,
Patrick Gendron
,
André Nantel
,
Sébastien Lemieux
,
Terry Roemer
,
Martine Raymond
(2009).
Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans
. Eukaryotic Cell.
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DOI
Marie-Hélène Fortier
,
Etienne Caron
,
Marie-Pierre Hardy
,
Grégory Voisin
,
Sébastien Lemieux
,
Claude Perreault
,
Pierre Thibault
(2008).
The MHC class I peptide repertoire is molded by the transcriptome
. The Journal of Experimental Medicine.
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DOI
Patricia Bouchard
,
Julie Lacroix-Labonté
,
Geneviève Desjardins
,
Philipe Lampron
,
Véronique Lisi
,
Sébastien Lemieux
,
François Major
,
Pascale Legault
(2008).
Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme
. RNA (New York N.Y.).
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DOI
Martin Sauvageau
,
Michelle Miller
,
Sébastien Lemieux
,
Julie Lessard
,
Josée Hébert
,
Guy Sauvageau
(2008).
Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia
. Blood.
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DOI
Sadri Znaidi
,
Sandra Weber
,
Zin Osman Al-Abdin
,
Perrine Bomme
,
Saloua Saidane
,
Simon Drouin
,
Sébastien Lemieux
,
Xavier Deken De
,
François Robert
,
Martine Raymond
(2008).
Genomewide location analysis of Candida albicans Upc2p a regulator of sterol metabolism and azole drug resistance
. Eukaryotic Cell.
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DOI
Xu Deming
,
Jiang Bo
,
Ketela Troy
,
Lemieux Sebastien
,
Veillette Karynn
,
Martel Nick
,
Davison John
,
Sillaots Susan
,
Trosok Steve
,
Bachewich Catherine
,
Bussey Howard
,
Youngman Phil
,
Roemer Terry
(2007).
Genome-Wide Fitness Test and Mechanism-of-Action Studies of Inhibitory Compounds in Candida albicans
. PLOS Pathogens.
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DOI
Madeleine Héroux
,
Mireille Hogue
,
Sébastien Lemieux
,
Michel Bouvier
(2007).
Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1
. The Journal of Biological Chemistry.
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DOI
Hu Wenqi
,
Sillaots Susan
,
Lemieux Sebastien
,
Davison John
,
Kauffman Sarah
,
Breton Anouk
,
Linteau Annie
,
Xin Chunlin
,
Bowman Joel
,
Becker Jeff
,
Jiang Bo
,
Roemer Terry
(2007).
Essential gene identification and drug target prioritization in Aspergillus fumigatus
. PLoS pathogens.
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DOI
Sébastien Lemieux
(2006).
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
. BMC Bioinformatics.
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DOI
Sébastien Lemieux
,
François Major
(2006).
Automated extraction and classification of RNA tertiary structure cyclic motifs
. Nucleic Acids Research.
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DOI
Roemer Terry
,
Jiang Bo
,
Davison John
,
Ketela Troy
,
Veillette Karynn
,
Breton Anouk
,
Tandia Fatou
,
Linteau Annie
,
Sillaots Susan
,
Marta Catarina
,
Martel Nick
,
Veronneau Steeve
,
Lemieux Sebastien
,
Kauffman Sarah
,
Becker Jeff
,
Storms Reginald
,
Boone Charles
,
Bussey Howard
(2003).
Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery
. Molecular Microbiology.
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DOI
Sébastien Lemieux
,
François Major
(2002).
RNA canonical and non-canonical base pairing types - a recognition method and complete repertoire
. Nucleic Acids Research.
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