Lemieux's Lab
Lemieux's Lab
News
Members
Projects
Publications
Collaborations
In the media
Contact us
English
Français
article-journal
BamQuery: a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
MHC-I-associated peptides deriving from non-coding genomic regions and mutations can generate tumor-specific antigens, including …
Maria Virginia Ruiz Cuevas
,
Marie-Pierre Hardy
,
Jean-David Larouche
,
Anca Apavaloaei
,
Eralda Kina
,
Krystel Vincent
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Pierre Thibault
,
Sébastien Lemieux
,
Claude Perreault
,
Gregory Ehx
Cite
Code
DOI
BamQuery
BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
MHC-I-associated peptides deriving from non-coding genomic regions and mutations can generate tumor-specific antigens, including …
Ruiz Virginia Maria Cuevas
,
Marie-Pierre Hardy
,
Jean-David Larouche
,
Anca Apavaloaei
,
Eralda Kina
,
Krystel Vincent
,
Patrick Gendron
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Pierre Thibault
,
Sébastien Lemieux
,
Claude Perreault
,
Gregory Ehx
Cite
DOI
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
Previous reports showed that mouse vaccination with pluripotent stem cells (PSCs) induces durable anti-tumor immune responses via T …
Anca Apavaloaei
,
Leslie Hesnard
,
Marie-Pierre Hardy
,
Basma Benabdallah
,
Gregory Ehx
,
Catherine Thériault
,
Jean-Philippe Laverdure
,
Chantal Durette
,
Joël Lanoix
,
Mathieu Courcelles
,
Nandita Noronha
,
Dev Kapil Chauhan
,
Sébastien Lemieux
,
Christian Beauséjour
,
Mick Bhatia
,
Pierre Thibault
,
Claude Perreault
Cite
DOI
Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia
Early T-cell development is precisely controlled by E proteins, that indistinguishably include HEB/TCF12 and E2A/TCF3 transcription …
T. F. Diogo Veiga
,
Mathieu Tremblay
,
Bastien Gerby
,
Sabine Herblot
,
André Haman
,
Patrick Gendron
,
Sébastien Lemieux
,
Carlos Juan Zúñiga-Pflücker
,
Josée Hébert
,
Paul Joseph Cohen
,
Trang Hoang
Cite
Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells
The sensitivity and depth of proteomic analyses are limited by isobaric ions and interferences that preclude the identification of low …
Zhaoguan Wu
,
Éric Bonneil
,
Michael Belford
,
Cornelia Boeser
,
Virginia Maria Cuevas Ruiz
,
Sébastien Lemieux
,
Jean-Jacques Dunyach
,
Pierre Thibault
Cite
DOI
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
Cholesterol homeostasis has been proposed as one mechanism contributing to chemoresistance in AML and hence, inclusion of statins in …
Jana Krosl
,
Marie-Eve Bordeleau
,
Céline Moison
,
Tara MacRae
,
Isabel Boivin
,
Nadine Mayotte
,
Deanne Gracias
,
Irene Baccelli
,
Vincent-Philippe Lavallée
,
Richard Bisaillon
,
Bernhard Lehnertz
,
Rodrigo Mendoza-Sanchez
,
Réjean Ruel
,
Thierry Bertomeu
,
Jasmin Coulombe-Huntington
,
Geneviève Boucher
,
Nandita Noronha
,
Caroline Pabst
,
Mike Tyers
,
Patrick Gendron
,
Sébastien Lemieux
,
Frederic Barabe
,
Anne Marinier
,
Josée Hébert
,
Guy Sauvageau
Cite
DOI
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly because of the lack of actionable immune targets. …
Gregory Ehx
,
Jean-David Larouche
,
Chantal Durette
,
Jean-Philippe Laverdure
,
Leslie Hesnard
,
Krystel Vincent
,
Marie-Pierre Hardy
,
Catherine Thériault
,
Caroline Rulleau
,
Joël Lanoix
,
Éric Bonneil
,
Albert Feghaly
,
Anca Apavaloaei
,
Nandita Noronha
,
M. Céline Laumont
,
Jean-Sébastien Delisle
,
Luca Vago
,
Josée Hébert
,
Guy Sauvageau
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
Cite
DOI
CAMAP - Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and neoplastic cells by CD8 T cells. However, …
Tariq Daouda
,
Maude Dumont-Lagacé
,
Albert Feghaly
,
Yahya Benslimane
,
Rébecca Panes
,
Mathieu Courcelles
,
Mohamed Benhammadi
,
Lea Harrington
,
Pierre Thibault
,
François Major
,
Yoshua Bengio
,
Étienne Gagnon
,
Sébastien Lemieux
,
Claude Perreault
Cite
DOI
Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers Clinicians and Patients - Scoping Literature Review
Background - This study aims to identify a novel potential use for web portals in health care and health research - their adoption for …
Michael Lang
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
,
H. Ma'n Zawati
Cite
DOI
Most non-canonical proteins uniquely populate the proteome or immunopeptidome
Combining RNA sequencing, ribosome profiling, and mass spectrometry, we elucidate the contribution of non-canonical translation to the …
Maria Virginia Ruiz Cuevas
,
Marie-Pierre Hardy
,
Jaroslav Hollý
,
Éric Bonneil
,
Chantal Durette
,
Mathieu Courcelles
,
Joël Lanoix
,
Caroline Côté
,
M. Louis Staudt
,
Sébastien Lemieux
,
Pierre Thibault
,
Claude Perreault
,
W. Jonathan Yewdell
PDF
Cite
Code
DOI
»
Cite
×