Geneviève Boucher

Latest

• Immunotherapeutic targeting of surfaceome heterogeneity in AML
• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Genetic characterization of ABT-199 sensitivity in human AML
• High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• The TCGA Meta-Dataset Clinical Benchmark
• Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity
• Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
• Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
• GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
• myCircos - Facilitating the Creation and Use of Circos Plots Online
• RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature
• The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
• Identification of small molecules that support human leukemia stem cell activity ex vivo
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia