Lemieux's Lab
Lemieux's Lab
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Claude Perreault
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Transposable elements regulate thymus development and function
BamQuery: a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
BamQuery - a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
The tumor-specific antigen landscape of acute myeloid leukemia
Two types of human TCR differentially regulate reactivity to self and non-self antigens
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
CAMAP - Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
Most non-canonical proteins uniquely populate the proteome or immunopeptidome
UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
Holographic Neural Architectures
Noncoding regions are the main source of targetable tumor-specific antigens
Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus
Warp - a method for neural network interpretability applied to gene expression profiles
Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
pyGeno - A Python package for precision medicine and proteogenomics
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
Transcriptome sequencing of neonatal thymic epithelial cells
MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
A comprehensive map of the mTOR signaling network
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules
The MHC class I peptide repertoire is molded by the transcriptome
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